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NFL · Week 7 · 2026·Updated

NFL Week 7 Picks: Every Game Against the Spread, With a Perfect Pair

The house desk's call on every game still to play: the side and the total at the number it called, how sure it is, and why. Beside each, the Perfect Pair, the player prop that wins for the same reason.

Every call on this page is graded against the final score, and the record is public in the OddsDesk app.

14 games still to play · 11 with a call · 13 with a Perfect Pair

GameSideTotalPerfect Pair
NE at CHICHI -3Under 50.5—PIT at NONO +3.5Under 44.5Tyler Shough Over 232.5 Pass YdsSF at ATLSF -3—George Kittle Over 5.5 Rec.CLE at TENTEN +1.5Under 38.5Cam Ward Under 196.5 Pass YdsIND at MININD +6.5—Jonathan Taylor Over 18.5 Rush Att.MIA at NYJMIA +4.5Under 38.5Garrett Wilson Over 5.5 Rec.TB at CARNo play—Chuba Hubbard Over 17.5 Rush Att.CIN at BALNo play—Tee Higgins Over 67.5 Rec. YdsNYG at HOUNYG +10—Malik Nabers Over 69.5 Rec. YdsDEN at ARIARI +4.5Under 43.5Trey McBride Over 7.5 Rec.GB at DETDET -3Under 53.5Jahmyr Gibbs Over 20.5 Rush Att.LA at LVLV +4.5—Brock Bowers Over 5.5 Rec.KC at SEAKC +2.5Over 42.5Kenneth Walker Over 19.5 Rush Att.DAL at PHINo play—Javonte Williams Over 16.5 Rush Att.

Thursday, October 22

8:15 PM ET · Amazon Prime VideoNE 4-2 · CHI 4-2

New England Patriots at Chicago Bears

Chicago's elite pass rush will overwhelm New England's heavily depleted offensive line.

SpreadChicago Bears -3High

Fade the Highlight Reel fired on CHI with 73% tickets on NE, supported by Chicago's #2 pass rush facing NE's depleted offensive line.

TotalUnder 50.5Medium

Sagarin projects 38.31 (12.19 points under market) while grass (52.41% under) and primetime (55.05% under) environment gates clear.

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Sunday, October 25

9:30 AM ET · NFL NetworkPIT 4-2 · NO 2-4

Pittsburgh Steelers at New Orleans Saints

Saints dominate late downs and red zone while Pittsburgh faces major regression.

SpreadNew Orleans Saints +3.5High

New Orleans holds elite high-leverage advantages in red zone EPA (+0.306 vs -0.131) and 3rd down rate (0.425 vs 0.333) against an overvalued Pittsburgh team due for heavy regression.

TotalUnder 44.5Low

Power Ratings projects 35.73 total points behind two sub-zero EPA passing offenses, though Sagarin's conflicting 51.47 projection caps confidence.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Tyler Shough Over 232.5 Pass Yds-118High

Facing a bottom-tier PIT pass rush generating only 0.177 pressure, Shough clears 232.5 passing yards as NO dictates tempo with 66.8 plays.

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1:00 PM ET · FOXSF 6-0 · ATL 2-4

San Francisco 49ers at Atlanta Falcons

Purdy's elite down-to-down efficiency outlasts severe receiver attrition against Atlanta's secondary.

SpreadSan Francisco 49ers -3Low

Purdy's 0.316 EPA and SF's league-leading 0.519 EDSR survive receiver injuries against an Atlanta defense missing key cornerbacks.

The Perfect Pairing

The player prop that wins for the same reason the call does.

George Kittle Over 5.5 Rec.-105Low

With Mike Evans and Deebo Samuel Sr. Out, Kittle absorbs intermediate targets against an Atlanta defense missing top cornerbacks.

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1:00 PM ET · CBSCLE 4-2 · TEN 1-5

Cleveland Browns at Tennessee Titans

Cleveland's inflated record and missing backfield meet an undervalued Titans home dog.

SpreadTennessee Titans +1.5High

Fade the Highlight Reel fires against 75% public ticket split, backed by Power Ratings projecting TEN -3.86 and Cleveland's +2.1 pythagorean luck surplus.

TotalUnder 38.5High

Power Ratings projects 30.34 and Sagarin projects 32.2, combining with bottom-tier offensive EPAs (-0.087 and -0.149) for a massive edge on the under.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Cam Ward Under 196.5 Pass Yds-116High

Facing a Cleveland secondary allowing 5.5 yards per pass, Ward's -0.198 pass EPA and slow 2.96s release fall well short of 196.5 passing yar

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1:00 PM ET · CBSIND 2-4 · MIN 5-0

Indianapolis Colts at Minnesota Vikings

Minnesota's dead-last early-down and red-zone offense cannot cover nearly a touchdown.

SpreadIndianapolis Colts +6.5High

Fade the Highlight Reel fired with 51% of tickets on MIN while Vikings rank 32nd in EDSR (0.321) and red-zone EPA (-0.344).

The Perfect Pairing

The player prop that wins for the same reason the call does.

Jonathan Taylor Over 18.5 Rush Att.-118High

Taylor carries a 0.739 team carry share and keeps heavy volume as Indianapolis controls tempo and keeps the game script tight.

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1:00 PM ET · CBSMIA 0-5 · NYJ 2-4

Miami Dolphins at New York Jets

Public backing of New York creates inflated line value on Miami plus the points.

SpreadMiami Dolphins +4.5High

Fade the Highlight Reel fires with 58% of public tickets on NYJ and fewer than three opposing votes.

TotalUnder 38.5Medium

Power Ratings projects a 32.53 total against market 38.5, reinforced by NYJ's #31 red-zone EPA.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Garrett Wilson Over 5.5 Rec.-141High

With Hall and Mitchell out, Wilson's 0.704 WOPR dominates target volume against Miami's secondary allowing a 0.694 completion rate.

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1:00 PM ET · FOXTB 1-5 · CAR 3-2

Tampa Bay Buccaneers at Carolina Panthers

Tampa Bay's quarterback injury structurally voids the board.

No playPass

TB starting QB Baker Mayfield ruled Out (thumb), invalidating baseline offensive and total projections

One edge here

The desk passed on the spread and the total. This is the bet it would make.

Chuba Hubbard Over 17.5 Rush Att.-101Medium

Hubbard commands a dominant 0.726 carry share and projects for heavy volume against a backup quarterback script.

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1:00 PM ET · CBSCIN 3-2 · BAL 4-2

Cincinnati Bengals at Baltimore Ravens

Lamar Jackson's confirmed absence structurally breaks baseline efficiency models.

No playPass

Starting QB Lamar Jackson is Out (ankle), invalidating Baltimore's baseline offensive EPA and passing metrics.

One edge here

The desk passed on the spread and the total. This is the bet it would make.

Tee Higgins Over 67.5 Rec. Yds-114Medium

Higgins commands an elite 0.644 WOPR and Burrow releases in 2.57s against a Baltimore defense yielding 63.6% completions.

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1:00 PM ET · FOXNYG 3-2 · HOU 2-4

New York Giants at Houston Texans

Houston's anemic red-zone offense cannot justify laying double digits against New York.

SpreadNew York Giants +10Medium

Model consensus projects margin at HOU -3.2 to -4.92, yielding a 5+ point edge over an inflated double-digit line.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Malik Nabers Over 69.5 Rec. Yds+120Medium

Nabers' extreme 0.69 WOPR ensures heavy passing volume against a Houston secondary conceding a 0.653 completion rate allowed.

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4:05 PM ET · CBSDEN 4-2 · ARI 2-4

Denver Broncos at Arizona Cardinals

Arizona's passing stability and Denver's regressing one-score luck expose a false road favorite.

SpreadArizona Cardinals +4.5High

Fade the Highlight Reel fires at HIGH on Arizona +4.5 against 63% tickets on Denver, backed by a +1.1 Pythagorean luck gap.

TotalUnder 43.5Medium

Power Ratings projects 36.25 points from Denver's 57.0 plays per game, supported by Arizona's -0.177 red-zone EPA and natural grass under trends.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Trey McBride Over 7.5 Rec.+106High

Trey McBride's 0.285 target share and elite volume attack a Denver secondary missing safety Talanoa Hufanga to easily top 7.5 catches.

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4:25 PM ET · FOXGB 4-2 · DET 3-2

Green Bay Packers at Detroit Lions

Detroit's early-down dominance and red-zone efficiency expose Green Bay's inflated record.

SpreadDetroit Lions -3Medium

Detroit's elite early-down success (0.504) and red-zone conversion (+0.322) dominate Green Bay's stalling offense (-0.197 RZ EPA) and regress Green Bay's +0.9 Pythagorean win luck.

TotalUnder 53.5Medium

Power Ratings (49.91) and Sagarin (49.82) both project a total well below 53.5, driven by Green Bay's 5.1 yards per pass allowed and poor red-zone finishing.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Jahmyr Gibbs Over 20.5 Rush Att.-106Medium

Leading game script feeds Gibbs's 0.82 carry share to run out the clock against Green Bay.

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4:25 PM ET · FOXLA 2-4 · LV 3-3

Los Angeles Rams at Las Vegas Raiders

Depleted Rams front and secondary leave road favorite vulnerable against Cousins and Bowers.

SpreadLas Vegas Raiders +4.5Low

Power Ratings projects LV -5.55 and Cousins outpaces Stafford in EPA (0.183 vs 0.074) while LA defensive attrition blunts pressure.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Brock Bowers Over 5.5 Rec.-131Low

Clean pockets against LA's depleted front funnel Kirk Cousins' targets directly to Brock Bowers over 5.5 receptions.

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8:20 PM ET · NBC/PeacockKC 5-0 · SEA 3-3

Kansas City Chiefs at Seattle Seahawks

Mahomes' quick release and early-down dominance expose Seattle's porous pass protection.

SpreadKansas City Chiefs +2.5Medium

KC holds overwhelming EPA (+0.155 vs -0.076) and EDSR (0.496 vs 0.420) advantages while Darnold's 3.25s release exposes Seattle's 31st-ranked pass protection.

TotalOver 42.5Medium

Power Ratings (63.26) and Sagarin (47.01) both project well above the market line against Seattle's vulnerable secondary and pass protection.

The Perfect Pairing

The player prop that wins for the same reason the call does.

Kenneth Walker Over 19.5 Rush Att.-105Medium

Kenneth Walker III commands a 0.763 carry share with +0.118 EPA/rush and will see elevated volume in positive game script.

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Monday, October 26

8:15 PM ET · ABC/ESPNDAL 2-4 · PHI 2-4

Dallas Cowboys at Philadelphia Eagles

Philadelphia quarterback Jalen Hurts on IR triggers a mandatory structural pass.

No playPass

Starting QB Jalen Hurts is on IR (calf), invalidating all baseline EPA and passing metrics.

One edge here

The desk passed on the spread and the total. This is the bet it would make.

Javonte Williams Over 16.5 Rush Att.-115Medium

Williams commands a 0.697 carry share facing a heavily depleted Philadelphia roster, setting up elevated rushing volume in a positive game s

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Also this week: College Football picks · News